The ability to achieve strong molecular recognition in water is a key challenge for supramolecular chemistry. Supramolecular chemistrygeneral principles and selected. Anion recognition as a supramolecular switch of cell. Gale and others published anion recognition in supramolecular chemistry find, read and cite all the research you. A texassized molecular box that forms an anioninduced supramolecular necklace. In the second part those will be illustrated by simple examples from our laboratories. Anion recognition due to the critical role of negatively charged species in numerous biological, environmental, chemical and medicinal processes, anion receptors and transporters play an important role in supramolecular chemistry 17,29.
These synthetic supramolecular receptors use reversible, mostly noncovalent interactions to select anions. The last three years of this project have focused on the basic chemical aspects of anion receptor design of functional ph independent systems, with the ultimate goal of targeting the selective binding of sulfate, as well as design of separations strategies for selective and efficient removal of targeted anions. Supramolecular chemistry of anions and macrocycles books and chapters. Supramolecular catalysis of phosphoryl anion transfer processes 421 mir wais hosseini, universite louis pasteur, strasbourg, france 11. Anion recognition properties of pyridine2,6dicarboxamide.
The chemical instability of heavier chalcogen derivatives may in part be responsible for the lack of progress. Special issue applications of supramolecular anion. The recognition of anions in water remains a key challenge in modern supramolecular chemistry, and is essential if proposed applications in biological, medical, and environmental arenas that typically require aqueous conditions are to be achieved. Supramolecular chemistry is the study of the structures and functions of the supermolecules that result from binding substrates to molecular receptors. Fluoride anions are an important target in supramolecular chemistry due to the importance of fluoride in biological and medical processes.
Anion recognition in supramolecular chemistry request pdf. Applications of supramolecular anion recognition chemical. The positive role of fluoride in dental health is well known e. Synthesis and anion recognition hiromitsu maeda acyclic oligopyrrolic anion receptors jeffery t. Supramolecular chemistry is the chemistry of the intermolecular bond, cover. Anion sensing by discrete molecular receptors relies on the fact that the recognition of a given anion by a receptor can induce a response, be it an optical color change or. Written by a group comprising pioneering researchers from the united states and europe, supramolecular chemistry of anions covers all theoretical and practical aspects of anion complexation, from. Thus, diverse anion receptors based on 1,2,3triazolium recog. Herein we present a novel approach to control the cell uptake of oligoarginine cpps based on the formation of a hostguest supramolecular complex involving an anion recognition process.
The chemical recognition of anions has progressed in leaps and. The strength of the forces responsible for spatial organization of the system range from weak intermolecular forces, electrostatic charge, or hydrogen bonding to strong covalent bonding, provided that the electronic coupling strength remains small relative. Applications of supramolecular anion recognition acs publications. In particular, the synthesis and investigation of various artificial systems based on this concept that are capable of potent and selective molecular recognition of anions in a face of their. However, anion supramolecular chemistry has developed substantially beyond anion recognition, and now encompasses a diverse range of disciplines. Biomimetic macrocyclic receptors for carboxylate anion recognition based on clinked peptidocalix4arenes. Free download supramolecular chemistry 2nd edition in pdf. Molecular recognition plays an important role in biological systems and is observed in between receptorligand, antigenantibody, dnaprotein, sugarlectin, rnaribosome, etc. Two threadshaped cations, pyridinium nicotinamide and imidazolium, as their chloride and hexafluorophosphate salts, were studied with regards to complexation with hydrogenbonddonating acyclic and macrocyclic ligands. A texassized molecular box that forms an anioninduced. Anion recognition in supramolecular chemistry philip a. Anion recognition in supramolecular chemistry springerlink. Davis anion binding and transport by prodigiosin and its analogs hemraj juwarker jaemin suk kyusung.
Bolyai university, department of chemistry and csoomc, 11 arany janos, 400028, clujnapoca, cluj, romania. Synthesis of receptors, biological receptors and metallareceptors, the energetics of anion binding, molecular structures of anion complexes, sensing devices are presented and computational studies. Anion recognition in supramolecular chemistry topics in heterocyclic chemistry 9783642154430. Building on the pioneering work in supramolecular chemistry from the last 20 years or so, this monograph addresses new and recent approaches to anion coordination chemistry. Davis anion binding and transport by prodigiosin and its analogs. Supramolecular chemistry of anions xxiv international symposium on macrocyclic chemistry, bellaterra barcelona july 1823, 1999, plenary lecture. Perrhenate and pertechnetate anion recognition properties of cyclo8pyrrole. An important example of molecular recognition is the antibiotic vancomycin that selectively binds with the peptides with terminal dalanyldalanine in bacterial cells through five hydrogen bonds.
Thermodynamics of anion binding by chalcogen bonding. Pdf supramolecular chemistry and selfassembly special. Supramolecular anion chemistry is a topical area of research with a large number of organic and coordination structures developed for the recognition, sensing, and transport of anions. Free download supramolecular chemistry 2e chemistry. Macropolycyclic receptors and coreceptors have been designed that form cryptate inclusion complexes and display molecular recognition towards spherical, tetrahedral, and linear substrates of various. The major thrust of this project, led by the university of kansas prof. In the designed construction of coordination networks, it is of interest to determine the highest ligation number hln of simple inorganic polyatomic anions.
Welcome,you are looking at books for reading, the supramolecular chemistry of anions, you will able to read or download in pdf or epub books and notice some of author may have lock the live reading for some of country. Supramolecular chemistry is the science that bridges the gap between the world of. This article is part of the 2015 supramolecular chemistry special issue. Whitea the interaction of tetratopic amidiniumcontaining receptors with terephthalate anions leads to porous. The application of chalcogen bonding chb to anion recognition is an underdeveloped area of hostguest supramolecular chemistry. His research interests focus on the supramolecular chemistry of anionic species and, in particular, the molecular recognition, sensing, and lipid bilayer transport of anions. Recognition of ammonium ions and related substrates.
Sulfatetemplated 2d anionlayered supramolecular self. Covalent polymers containing discrete heterocyclic anion receptors. Over the past two decades, anion recognition and coordination has evolved as the topic of significant interest in the domain of supramolecular chemistry 1234567 as anions exist. Whitea aresearch school of chemistry, australian national university 7 sullivans creek road, acton, 2601, act, australia email. Introduction encumbered by the difficulties associated with binding anions in protic solvents, the field of anion recognition has lagged behind that of cation recognition. Therefore it need a free signup process to obtain the book. He has won a number of research prizes including the rsc 2014 supramolecular chemistry award, a royal society wolfson research merit award, and the rsc corday morgan medal. Now, halogen bonding the attractive interaction between an electrondeficient. Supramolecular chemistry of selective anion recognition.
Supramolecular chemistry of anions download pdfepub. Supramolecular chemistry is the science that bridges the gap. H adade, aanamariaterec, a elena bogdan a and ion grosu a ababe. Kindly follow the instructions to unlock the download link. Reflection of such actions and mechanisms of naturally occurred molecular machinery let to constantly develop the domain of supramolecular chemistry. Sometime download links are not visible on mobile devices, so if you face this issue, kindly do visit this page via laptopdesktop computer. Supramolecular chemistry of selective anion recognition for anions of environmental relevance project id. Anion recognition in supramolecular chemistry topics in. In the context of supramolecular chemistry, the coordination concept as commonly applied to metal ions has been extended to polyatomic anionic species 1. Supramolecular chemistry is an uptodate, integrated textbook that tells the. The strategy relies on the encapsulation of a negatively charged pyranine attached to the nterminus of a peptide containing an octaarginine cpp. Pdf calixnpyrroles as anion and ionpair complexants. Anion coordination chemistry and the recognition of anionic sub.
Anion recognition properties of pyridine2,6dicarboxamide and isophthalamide derivatives containing ltryptophan moieties. Ditopic molecular architectures for the recognition of anionic. A synthetic supramolecular receptor for hydrosulfide anion. Applications of supramolecular anion recognition request pdf. Supramolecular chemistry is chemistry beyond the molecule the chemistry of molecular assemblies and intermolecular bonds. Kristin bowmanjames, university of kansas bruce moyer, oak ridge national laboratory research objective this project had as its original focus the design and synthesis of polyammonium macrocyclic receptors.
Perrhenate and pertechnetate anion recognition properties. Supramolecular chemistry and selfassembly special feature. The cell internalization of designed oligoarginine peptides equipped with six glutamic acid residues and an anionic pyranine at the nterminus is triggered upon addition of a supramolecular host. Kristin bowmanjames, entails an exploration of the basic determinants of anion recognition and their application to the design, synthesis, and testing of novel sulfate extractants. It is one of todays fastest growing disciplines, crossing a range of subjects from biological chemistry to materials science. Supramolecular chemistry is the domain of chemistry concerning chemical systems composed of a discrete number of molecules. Davis anion binding and transport by prodigiosin and its analogs hemraj juwarker jaemin suk kyusung jeong indoles and related heterocycles pavel anzenbacher jr. Supramolecular hosts have been developed to selectively bind a variety of anionic species in solution, ranging from inorganic phosphates and phosphorylated biomolecules, to halides, to other anions of environmental andor biological relevance. This host binds specifically to the pyranine moiety.
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