Cutaneous lesions are classified as specific and nonspecific. The discoid lupus erythematosus affects the skin only. The variety of clinical manifestations of the disease is reflected in the broad spectrum of laboratory patterns. Abstract discoid lupus erythematosus is a chronic, autoimmune skin disease characterized by welldefined, erythematosus, scaly. Summary the systemic lupus erythematosus sle is a disease that affects many organ systems, in its pathogenesis are involved multiple auto antibodies, and its etiology remains unknown. Nowadays several therapeutic interventions are available to the treatment of cutaneous lupus. Lupus erythematosus le panniculitis profundus is an unusual clinical variant of lupus erythematosus in which the cutaneous inflammatory reaction occurs primarily in the deeper corium. Skin lesions are classified according to the clinical and histopathologic features, which are of great relevancy for the management of the disease.
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